Since 2019, Team CADASIL has participated in the University of Pennsylvania's Million Dollar Bike Ride — an annual cycling event that raises money for rare disease research. Each year, our riders hit the road (and the stationary bike) to fund groundbreaking CADASIL research grants. Below is our complete history.
Team CADASIL returned for another year of pedaling for progress. The community rallied once again to push fundraising totals higher and bring more attention to CADASIL research.
Title: Small Molecule Inhibiiton of Notch3 Confomational Alterations
Grant Amount:$101,776
Funding Period: Feb 1, 2025 - Jan 31, 2026
Team CADASIL took part in the 2024 MDBR, continuing the annual tradition of raising funds specifically designated for CADASIL pilot research grants through the University of Pennsylvania program.
Title:Immunotherapy and Improved Diagnosis and Prognosis of the Small Vessel Disease CADASIL
Grant Amount:$109,856
Funding Period:Feb 1,2024 - Jan 31,2025
The 2023 ride brought renewed energy to the team. Funds raised went directly toward MDBR pilot research grants, keeping CADASIL science moving forward.
Title:Advance in PIP2 Treatement to Restore Capillary Blood Flow
Grant Amount:$117,734
Funding PeriodFeb 1,2023- Jan 31,2024
2022 marked another strong showing for Team CADASIL. Riders and supporters across the community helped push cumulative totals higher, funding meaningful pilot research.
Title:single-Nuclei RNA-Seq for CADASIL Understanding and Therapeutic Target Discover
Grant Amount:$60,228
Funding Perios:Feb 1, 2022 - Jan 31,2023
2022 marked another strong showing for Team CADASIL. Riders and supporters across the community helped push cumulative totals higher, funding meaningful pilot research.
Title:Modeling CADASIL iwth Patient IPSC BASED 3D Vessel-on-Chip
Grant Amount:$60,228
Funding Perios:Feb 1, 2022 - Jan 31,2023
Awardee:Masay Koide, University of Vermont Larner College of Medicine
Title:HB-EGF/EFR Signaling in Capllary Dysfunction in CADASILMbr>
Grant Amount:$82,795
Funding Period:Feb 1, 2021-Jan 31, 2022
Despite the global pandemic, Team CADASIL showed up — virtually. The 2020 MDBR moved online, but our riders and supporters didn't miss a beat, demonstrating the resilience of this community.
2019 marked Team CADASIL's very first participation in the Million Dollar Bike Ride. This inaugural effort planted the seed for what has grown into a beloved annual tradition — and an important funding pipeline for CADASIL research.
Moments from the Ride
Join the Ride — or Support a Rider
Every dollar raised through the Million Dollar Bike Ride goes directly to CADASIL pilot research grants. Sign up to ride, or donate to support someone already on the team.